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Kras mutant phenotype occurs in EYFP+ and in EYFP– cells in Ptf1aCreERTMLSL-KrasG12DR26REYFPmice, reflecting broader recombination of the LSL-KrasG12Dallele than of the R26REYFPallele. Note the PanIN-like lesions with tall columnar morphology and basal nuclei, some of which are positive for EYFP (brown) and some of which are negative (arrows).
