Fig. 1.

3D-structures of reference drugs: a phenoxy benzamine, b verapamil, c calmozolium, d domperidone, e ranitidine, f piranzapine, g atropine, h loperamide, i omeprazole and (j) pyrilimine, drawn through Chem Sketch 2015, 2.5 and saved in PDB format through Biovia Discovery Studio 2016. Atoms are shown by colors; gray color (carbon atoms), white color (hydrogen atoms), red color (oxygen atoms), blue color (nitrogen atoms), dark red (bromine), and yellow color (sulfur atoms)