Table 4.
Top 100 lung cancer-associated miRNAs predicted by IRFMDA after deleting all validated miRNA-lung cancer associations in the HMDD (v2.0). The top 1–25, top 26–50, top 51–75, and top 76–100 miRNAs associated with lung cancer are listed in the first, third, fifth and seventh column respectively. As one can see, 100 of the top 100 miRNAs associated with lung cancer predicted by IRFMDA were validated by HMDD v3.0 or dbDEMC v2.0. “D” represents “dbDEMC v2.0”, “H” represents “HMDD v3.0”
| miRNA | Evidence | miRNA | Evidence | miRNA | Evidence | miRNA | Evidence |
|---|---|---|---|---|---|---|---|
| hsa-let-7a | D & H | hsa-mir-19b | D & H | hsa-mir-30b | D & H | hsa-mir-449a | D & H |
| hsa-let-7 g | D & H | hsa-mir-20a | D & H | hsa-let-7b | D & H | hsa-mir-93 | D |
| hsa-mir-124 | D & H | hsa-mir-375 | D & H | hsa-let-7c | D & H | hsa-let-7f | D & H |
| hsa-mir-133b | D & H | hsa-mir-486 | D & H | hsa-mir-133a | D & H | hsa-mir-107 | D & H |
| hsa-mir-143 | D & H | hsa-mir-497 | D & H | hsa-mir-142 | D & H | hsa-mir-128 | D & H |
| hsa-mir-146b | D & H | hsa-mir-92a | D & H | hsa-mir-200b | D & H | hsa-mir-302c | D |
| hsa-mir-148a | D & H | hsa-mir-183 | D & H | hsa-mir-200a | D & H | hsa-mir-135a | D & H |
| hsa-mir-181a | D & H | hsa-mir-139 | D & H | hsa-mir-146a | D & H | hsa-mir-339 | D |
| hsa-mir-182 | D & H | hsa-mir-372 | D & H | hsa-mir-221 | D & H | hsa-mir-423 | D & H |
| hsa-mir-199a | D & H | hsa-mir-373 | D & H | hsa-mir-27a | D & H | hsa-mir-137 | D |
| hsa-mir-223 | D & H | hsa-mir-106b | D | hsa-mir-34a | D & H | hsa-mir-520d | D & H |
| hsa-mir-29c | D & H | hsa-mir-92b | D | hsa-mir-141 | D & H | hsa-mir-205 | D & H |
| hsa-mir-31 | D & H | hsa-mir-452 | D | hsa-mir-16 | D & H | hsa-mir-708 | D |
| hsa-mir-34c | D & H | hsa-mir-302d | D | hsa-mir-135b | D & H | hsa-mir-191 | D & H |
| hsa-mir-7 | D & H | hsa-let-7d | D & H | hsa-mir-18b | D & H | hsa-mir-378a | D |
| hsa-mir-15a | D & H | hsa-mir-429 | D | hsa-mir-338 | D & H | hsa-let-7i | D & H |
| hsa-mir-195 | D & H | hsa-mir-302a | D | hsa-mir-152 | D & H | hsa-mir-200c | D & H |
| hsa-mir-125a | D & H | hsa-mir-32 | D & H | hsa-mir-215 | D & H | hsa-mir-29b | D & H |
| hsa-mir-125b | D & H | hsa-mir-1 | D & H | hsa-mir-367 | D | hsa-mir-224 | D & H |
| hsa-mir-126 | D & H | hsa-mir-196a | D & H | hsa-mir-122 | D & H | hsa-mir-29a | D & H |
| hsa-mir-145 | D & H | hsa-mir-25 | D | hsa-mir-134 | D & H | hsa-mir-30c | D & H |
| hsa-mir-155 | D & H | hsa-mir-34b | D | hsa-mir-130a | D & H | hsa-mir-140 | D & H |
| hsa-mir-17 | D & H | hsa-mir-342 | D | hsa-mir-574 | D & H | hsa-mir-193a | D & H |
| hsa-mir-18a | D & H | hsa-mir-218 | D | hsa-mir-206 | D & H | hsa-mir-193b | D |
| hsa-mir-199b | D & H | hsa-mir-328 | D | hsa-mir-204 | D | hsa-mir-30e | D & H |