Fig. 1.
Gene-obesity interactive effects on the risk of dyslipidemia. The bar plots on the lower side of each graph describe the OR as the ratio of the probability of dyslipidemia occurring in each exposed group (G ≠ 0 or E ≠ 0) to the probability in a nonexposed group (G = 0 and E = 0). The upper plots, on the other hand, show multiplicative effects of obesity traits for each genetic group. The figure above describes the estimated OR of each lipid abnormality due to the interplay between HMGCR and abdominal obesity based on WHR (A), LOC101928271 and overweight class 1 (B), BUD13 and abdominal obesity class 1 (C), BUD13 and abdominal obesity class 2 (D), LOC101929680/SCN1A and obesity (E), APOA5 and abdominal obesity based on WHR (F), and APOA5 and abdominal obesity based on WHR (G). Further details are provided in supplemental Table S4.
