Fig. 2.

Changes in lipid levels due to increments in BMI for each risk group. The participants in each study population were classified into three groups by the number of risk alleles on G×E markers: the low-risk group (individuals with no risk alleles), the high-risk group (individuals with at least one risk allele), and the higher-risk group (the upper 50% of the high-risk group). The figure above describes the trends of lipid levels due to an increment of 1 kg/m² in BMI for each subgroup. A: The differences in the decrement of HDL-C for each genetic subgroup were far clearer in the obese group than in the group with normal BMI. B: The differences in the increment of TG for each risk group were far clearer in the obese group than in the group with normal BMI; further details are presented in supplemental Table S5.