TABLE 1.
Basic characteristics of the participants in each Korean cohort
| Reference Set | Replication Set | |||
| Ansan Cohort | Ansung Cohort | Urban Cohort | Rural Cohort | |
| Participants | 4,236 | 3,606 | 3,436 | 4,736 |
| Age (years) | 50.1 ± 7.7 | 56.9 ± 8.8 | 52.7 ± 8.2 | 60.2 ± 9.3 |
| Sex, male (%) | 2,136 (50.4) | 1,531 (42.5) | 1,494 (43.5) | 1,914 (40.4) |
| BMI (kg/m2) | 24.5 ± 2.8 | 24.4 ± 3.2 | 23.9 ± 2.9 | 23.9 ± 3.2 |
| WC (cm) | 80.4 ± 7.9 | 85.6 ± 8.5 | 82.2 ± 8.8 | 83.5 ± 8.8 |
| HC (cm) | 94.1 ± 4.7 | 91.0 ± 5.5 | 95.3 ± 5.8 | 93.2 ± 6.6 |
| WHR | 0.85 ± 0.06 | 0.94 ± 0.06 | 0.86 ± 0.06 | 0.90 ± 0.06 |
| Total-C (mmol/l) | 5.11 ± 0.82 | 4.87 ± 0.82 | 5.13 ± 0.89 | 5.13 ± 0.96 |
| HDL-C (mmol/l) | 1.18 ± 0.24 | 1.17 ± 0.24 | 1.42 ± 0.34 | 1.18 ± 0.29 |
| LDL-C (mmol/l) | 3.18 ± 0.75 | 2.96 ± 0.75 | 3.08 ± 0.83 | 3.20 ± 0.88 |
| TG (mmol/l) | 1.64 ± 0.98 | 1.63 ± 1.00 | 1.37 ± 1.00 | 1.62 ± 1.09 |
| Remnant-C (mmol/l) | 0.75 ± 0.45 | 0.75 ± 0.46 | 0.63 ± 0.46 | 0.74 ± 0.50 |
LDL-C was calculated using the Friedewald’s formula for individuals with TG under 4.52 mmol/l; Remnant-C was determined as the level of Total-C minus HDL-C minus LDL-C. Detailed features stratified by obesity status into subgroups based on BMI, WC, and WHR are presented in supplemental Table S2.