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MIST1 expression plays a role in Paneth cell granule size and maturation. Transmission electron micrographs of crypts from jejunal tissue of (A) and (a) Mist1+/+ and (B) and (b) Mist1–/– mice showing ultrastructural characteristics of Paneth cells. (C) Quantification of Paneth cell granule size. n = 3 mice per group. **P <.01.
