Table 5.

Methodology used for insight assessment and brain imaging.

Brain imaging technique	Method of insight assessment			Total
	Participant-informant discrepancy score	Self-ratings versus performances	Clinical judgment
Structural*	6	2	1	9
Functional⁎⁎	1	1	3	5
Combined⁎⁎⁎	0	1	0	1
Total	7	4	4	15

No study used DTI, MEG, MRS or histological observations to explore any modality of lack of insight in FTD.

^⁎8 studies (88.89%) used MRI [Amanzio et al. (2016), Hornberger et al. (2014), Levy et al. (2018), Massimo et al. (2013), Rosen et al. (2010), Shany-Ur et al. (2014), Sollberger et al. (2014) and Zamboni et al. (2010)] and 1 (11.11%) used CT [Ichikawa et al. (2013)).

^⁎⁎All studies used either PET or SPECT [Bastin et al. (2012), McMurtray et al. (2006), Mendez and Shapira (2005), Miller et al. (1997) and Ruby et al. (2007)].

^⁎⁎⁎1 study used structural MRI, EEG and resting state functional MRI [Garcia-Cordero et al. (2016)].