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. 2019 Nov 26;13:74. doi: 10.3389/fncir.2019.00074

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Copyright © 2019 Inami, Tanihira, Kikuta, Ogasawara, Sobue, Kume, Osanai and Ohsawa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The active regions within the limbic structure in SNI mice compared with sham mice analyzed by AIM-MRI. Regions with significant shortening of T1 in SNI mice are indicated by the pseudo-colored regions over the T2-enhanced brain image template in coronal planes (n = 6 for sham, n = 6 for SNI). The active regions within the limbic structure are defined in text: nucleus accumbens (NAc), caudate-putamen (CPu), globus pallidus (GP), and ventral posterolateral nucleus of thalamus (VPL). The distance from bregma in mm is shown at the bottom. T, t-value; P, p-values.