TABLE 1.
Coordinates, statistical values, and T1 value of the active region in SNI compared with sham mice (n = 6) analyzed by AIM-MRI.
|
Coordinate (mm) |
Sham |
SNI |
||||
| Region | M-L | D-V | A-P | T1 (s) | T1 (s) | P |
| Limbic structure | ||||||
| Right NAc | –2.11 | 3.48 | 2.0 | 2.35 | 2.16 | <0.005 |
| Right CeA | –2.62 | 3.31 | 0.3 | 2.30 | 2.13 | <0.005 |
| Left PCC | 0.21 | 7.26 | –1.5 | 2.36 | 2.22 | <0.005 |
| Basal ganglia | ||||||
| Right CPu | –2.79 | 5.71 | 0.8 | 2.50 | 2.35 | <0.005 |
| Right GP | –2.62 | 3.82 | –0.3 | 2.23 | 2.09 | <0.01 |
| Right VPL | –2.79 | 4.51 | –1.3 | 2.20 | 2.13 | <0.005 |
| Cortex | ||||||
| Right Pir | –2.02 | 3.57 | 2.5 | 2.04 | 1.86 | <0.005 |
| Right IC | –2.02 | 4.25 | 2.3 | 2.38 | 2.29 | <0.025 |
| Right S2 | –3.91 | 5.11 | 0.3 | 2.52 | 2.41 | <0.005 |
| Left S2 | 4.51 | 5.63 | –0.8 | 2.67 | 2.51 | <0.005 |
M-L, medial – lateral (mm); D-V, dosal – ventral (mm); A-P, anterior – posterior (mm). The active regions are defined in the table, nucleus accumbens (NAc), caudate-putamen (CPu), central amygdala (CeA), globus pallidus (GP), ventral posterolateral nucleus of thalamus (VPL), posterior cingulate cortex (PCC), piriform cortex (Pir), insula cortex (IC), secondary somatosensory area (S2), sensory-motor cortex (S1, M1, and M2). t and p: t-values and p-values of Student’s t-test, respectively.