Skip to main content
. Author manuscript; available in PMC: 2019 Dec 3.
Published in final edited form as: Cell Rep. 2019 Nov 12;29(7):2016–2027.e4. doi: 10.1016/j.celrep.2019.10.021

Figure 1. Early Onset of Behavioral Deficits in Shank3B−/− Mice.

Figure 1.

(A) Total distance traveled for 30 min in the open field test by P21 and P60 WT and Shank3B−/− mice. Heatmap represents distance values normalized to P60 WT.

(B and C) Mean ± SEM of distance traveled by P15–P90 WT and Shank3B−/− mice during 30 min (B) in the open field arena or (C) in the center region of the arena.

(D) Mean ± SEM of fraction of distance traveled in the center versus total arena.

(E) Mean ± SEM number of wall rearing bouts per session.

(F) Mean ± SEM total time spent grooming.

(G) Mean ± SEM duration of individual grooming bouts.

(H) Mean ± SEM number of grooming bouts per session.

(I) Mean ± SEM latency to fall in the accelerating rotarod test.