Table 1. Screening of reaction conditions a .
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aReaction conditions: 1a (0.2 mmol), catalyst (0.02 mmol), ligand (0.024 mmol) and additive (1.0 equiv.) were stirred in solvent (2.0 mL) at 80 °C under O2.
bDetermined by 1H NMR analysis using 1,1,2,2-tetrachloroethane as the internal standard. The numbers in parentheses are isolated yields.
cUnder an argon atmosphere.
dNot detected.
eThis reaction was carried out under air.