Table 2 –
Functional connectivity z(r) values in the PPA subgroups
| PPA Subtype | Node Pairs | Left Hemisphere | Right Hemisphere |
|---|---|---|---|
| PPA-G | IFG-MTG | 0.23 ± .23* | 0.16 ± .20 |
| IFG-ATL | 0.14 ± .18 | 0.06 ± .16 | |
| MTG-ATL | 0.19 ± .22 | 0.14 ± .16 | |
| PPA-L | IFG-MTG | 0.22 ± .20* | 0.23 ± .19 |
| IFG-ATL | 0.13 ± .22 | 0.03 ± .17 | |
| MTG-ATL | 0.22 ± .16 | 0.18 ± .18 | |
| PPA-S | IFG-MTG | 0.21 ± .20* | 0.18 ± .21 |
| IFG-ATL | 0.01 ± .16* | −0.01 ± .14 | |
| MTG-ATL | 0.04 ± .15* | 0.12 ± .15 | |
significantly decreased versus controls after FDR correction for multiple comparisons (p < 0.05). p values (top to bottom): p = 0.001, 0.002, 0.002, 0.001, <0.0005. ANCOVA analyses showed that the IFG-MTG connection in PPA-G continued to be significantly decreased when cortical volume was included as a covariate (p=0.036). In PPA-L patients there was only a trend towards significance (p=0.082).