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. 2019 Nov 13;45(1):81–92. doi: 10.3892/ijmm.2019.4406

Figure 7.

Figure 7

CBX administration reversed the changes in the proportions of T lymphocyte subtypes in the lungs of MCT-treated rats. (A) Gating for T lymphocytes among mononuclear cells and representative flow cytometry plots of pulmonary T lymphocytes subtypes (CD4+ and CD8+). MCT-treated rats exhibited significantly increased levels of CD3+ and CD4+ T cell infiltration in the lungs. Intraperitoneal administration of CBX reversed the changes in the percentages of various T lymphocyte subpopulations in the lungs of the MCT-treated rats. (B) Bar graphs representing the proportions of various T cell subpopulations and CD4+/CD8+ T cell subset ratios. Data are presented as the mean ± standard error of the mean of 6 rats/group. **P<0.01 vs. control. #P<0.05 and ##P<0.01 vs. MCT-treated group. CBX, Carbenoxolone; CD, cluster of differentiation; CON, control; FITC, fluorescein isothiocyanate; PE, phycoerythrin; APC, allophy-cocyanin; MCT, monocrotaline; CON, control.