Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 13;45(1):81–92. doi: 10.3892/ijmm.2019.4406

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

CBX administration decreases the percentages of Cx43-expressing CD4⁺ and CD8⁺ T cells in the lung tissues of the MCT-treated rats. (A) Representative flow cytometry plots and (B) quantitative analysis demonstrating the proportions of CD4⁺Cx43⁺ or CD8⁺Cx43⁺ double-positive T cells were increased in lung tissues of MCT-treated rats compared with the control group. There was a significant decrease in the frequencies of CD4⁺Cx43⁺ and CD8⁺Cx43⁺ T cells in the MCT + CBX-treated rats compared with the MCT-treated rats. The frequencies of CD4⁺Cx43⁺ and CD8⁺Cx43⁺ T cells did not significantly differ between the lungs of control rats and the rats treated with a single intraperitoneal injection of CBX. Data are presented as the mean ± standard error of the mean of 6 rats/group. ^**P<0.01 vs. the control group. ^#P<0.05 vs. the MCT-treated rats. APC, allophycocyanin; CBX, carbenoxolone; CON, control; Cx, connexin; CD, cluster of differentiation; FITC, fluorescein isothiocyanate; MCT, monocrotaline.