Trial ID	Instrument	Dimensions (subscales) (no. of items)	Validated instrument	Answer options	Scores	Minimum score Maximum score	Weighting of scores	Direction of scales	Minimal important difference
DPP/DPPOS 2002	SF‐36 (G)	Physical functioning (PF) (10) Role‐physical (RP) (4) Bodily pain (BP) (2) General health (GH) (5) Vitality (VT) (4) Social functioning (SF) (2) Role‐emotional (RE) (3) Mental health (MH) (5)	Yes	Likert‐scale	Scores for dimensions Physical component summary (PCS) Mental component summary (MCS)	Minimum scores: 0 Maximum scores:100	No	Higher values mean better assessment	Minimal important difference was defined as HRQoL scores between groups differed by at least 3 %; In other publication (Marrero et al) minimal important difference is defined as two points on either PCS or MCS.
G: generic; HRQoL: health‐related quality of life; S: specific; SF: short‐form health survey.