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. 2019 Oct 31;45(1):45–52. doi: 10.3892/ijmm.2019.4388

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Copyright: © Jiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Abnormal expression of miR-342-3p and SOX6 in the kidney tissues of mice with diabetic nephropathy. (A and B) mRNA and protein expression of TGF-β1, FN and C-IV in the control and DKD groups. (B-D) Analysis of SOX6 expression level in the control and DKD groups. A significant increase in SOX6 expression at both the mRNA and protein level was observed in the DKD group, as compared with the control group. (E) Analysis of the miR-342-3p expression level in the control and DKD groups. A notable decrease in miR-342-3p expression was observed in the DKD compared with the control group. **P<0.01. SOX6, SRY-box 6; DKD, diabetic kidney disease; TGF-β1, transforming growth factor β1; FN, fibronectin; C-IV, collagen IV.