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. 2019 Nov 26;45(1):234–244. doi: 10.3892/ijmm.2019.4412

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Knockdown of SYT13 inhibits tumor growth in a mouse xenograft model. (A) The volume of tumors in shCtrl and shSYT13 groups was measured at 4, 7, 11, 14 and 17 days post-injection. (B) Mean weight of the tumors in the shCtrl and shSYT13 groups. (C) Macroscopic observation of tumors resected from mice in the shCtrl and shSYT13 groups. (D) The tumor sections were subjected to immunohistochemical staining using an antibody against Ki-67 (magnification, ×200). (E and F) The expression of SYT13 in the tumors was detected by (E) quantitative PCR analysis and (F) western blotting. Data are presented as the mean ± standard deviation (n≥3). ^*P<0.05, ^**P<0.01. SYT, synaptotagmin.