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Inflammatory signals which activate MDSCs and lead to their chemotaxis
| Accepted phenotyping of MDSCs in mice and humans | ||
|---|---|---|
| Mice | ||
| M-MDCS | PMN-MDSC | e-MDSC |
| CD11b+Gr-1midLy6ChiLy6G−CD49d+ | CD11b+Gr-1hiLy6ClowLy6G+CD49d− | poorly defined |
| Human | ||
| M-MDCS | PMN-MDSC | e-MDSC |
| CD11b+CD14+HLA-DRlow/−CD15− | CD11b+CD14−CD15+(or CD66b+) | Lin-(CD3/14/15/19/56)/HLA-DR−/CD33+ |
