Table 2. Fold-changes of 63 metabolites and their AUC values.
| Metabolite | Fold- change |
AUC | Metabolite | Fold- change |
AUC | Metabolite | Fold- change |
AUC |
|---|---|---|---|---|---|---|---|---|
| Amino acid | Nucleotides | L-palmitoylcarnitine | 1 | 0.416 | ||||
| Creatinine | 0.66*** | 0.745 | Hypoxanthine | 7.62*** | 0.859 | Dodecanoylcarnitine | 0.40*** | 0.887 |
| Sarcosine | 1.32** | 0.716 | Uric acid | 0.93* | 0.680 | Oleamide | 0.96 | 0.568 |
| 5-oxoproline (pyroglutamic acid) | 2.12*** | 0.968 | Uridine | 0.91 | 0.599 | Palmitic amide | 0.98 | 0.544 |
| L-Threonine | 1.08 | 0.527 | Organic compounds | 13Z-docosenamide | 0.86 | 0.572 | ||
| Betaine | 0.92 | 0.571 | Acetylcholine | 0.76** | 0.734 | Suberic acid | 1.02 | 0.62 |
| Histidine | 0.99 | 0.535 | Phenylsulfate | 2.12 | 0.510 | Octanoic acid (caprylic acid) | 1.62*** | 0.802 |
| L-Lysine | 0.94 | 0.543 | Salicylaldehyde | 1.13 | 0.595 | Myristic acid | 1.07 | 0.512 |
| Homocysteinesulfinic acid | 1.02 | 0.393 | Trigonelline | 3.14** | 0.713 | Palmitic acid | 0.87* | 0.654 |
| L-phenylalanine | 1.30*** | 0.838 | Taurine | 1.11 | 0.583 | LysoPC(16:0) | 1.25*** | 0.833 |
| Indoxyl sulphate | 2.74 | 0.642 | 3-Methoxy-4-hydroxyphenylethyleneglycol sulfate | 1.33 | 0.597 | LysoPC(16:1) | 1.26* | 0.683 |
| L-Tryptophan | 1.15 | 0.583 | p-Cresol sulfate | 0.47*** | 0.746 | LysoPC(18:0) | 1.34** | 0.713 |
| L-Isoleucine/Leucine | 1.32** | 0.728 | Pyrocatechol sulfate | 1.08 | 0.487 | LysoPC(18:1) | 1.18*** | 0.772 |
| 3-methyl-2-oxovaleric acid | 0.91 | 0.579 | Pyrogallol-2-O-sulphate | 1.79 | 0.574 | LysoPC(18:2) | 1.42*** | 0.848 |
| Bile acid | Bilirubin | 0.22*** | 0.943 | LysoPC(20:1) | 1.17* | 0.653 | ||
| Glycoursodeoxycholic acid | 2.62*** | 0.780 | Oxoadipic acid | 1.02 | 0.443 | LysoPC(22:6) | 1.47*** | 0.808 |
| Glycochenodeoxycholic acid | 4.46*** | 0.893 | Lipid | LysoPC(O-16:0) | 1.30*** | 0.761 | ||
| Tauroursodeoxycholic acid | 6.04*** | 0.892 | Docosahexaenoic acid | 0.53*** | 0.822 | LysoPE(16:0) | 1.15* | 0.683 |
| Vitamins and Cofactors | Cis-5-tetradecenoylcarnitine | 0.43*** | 0.842 | LysoPE(18:1) | 1.97*** | 0.833 | ||
| 1-methylnicotimanide | 0.56*** | 0.869 | Linoleyl carnitine | 1.35 | 0.593 | LysoPE(18:2) | 1.66*** | 0.795 |
| Carbohydrate | L-octanoylcarnitine | 0.41*** | 0.858 | LysoPE(20:4) | 1.34** | 0.685 | ||
| Glucose | 1.29* | 0.660 | Vaccenyl carnitine | 1.12 | 0.496 | LysoPE(22:6) | 1.1 | 0.577 |
| Energy | L-acetylcarnitine | 0.66*** | 0.784 | Sphingosine-1-phosphate | 1.65*** | 0.801 | ||
| Isocitric acid/citric acid | 0.62 | 0.614 | L-carnitine | 0.83* | 0.697 | |||
AUC; area under the curve
*p-value < 0.05
**p-value <0.01
***p-value <0.001.