Table 4.

Comparison of treatment modalities between r-axSpA and nr-axSpA: pooled analysis

Variable	N studies	r-axSpA		nr-axSpA		Rr (95% CI)	P value	I2
		N patients	Pooled percentage (95% CI)	N patients	Pooled percentage (95% CI)
NSAIDs	13	3365	73.5% (63.1 to 81.8)	1727	69.1% (55.5 to 80.0)	1.04 (0.96 to 1.12)	0.379	79.8%
csDMARDs	12	3179	29.6% (20.5 to 39.9)	1355	28.5% (21.9 to 36.2)	1.04 (0.83 to 1.29)	0.726	75.5%
bDMARDs	9	3834	28.7% (19.7 to 39.7)	1318	26.2% (16.1 to 39.6)	1.08 (0.89 to 1.32)	0.444	71.0%
Systemic glucocorticoids	8	2769	8.5% (5.2 to 13.4)	903	10.1% (8.2 to 12.3)	0.93 (0.73 to 1.18)	0.547	38.6%

1/13 studies for NSAIDs outcome are from RCTs; 1/12 studies for csDMARDs outcome are from RCTs; 1/9 studies for bDMARDs outcome are from RCTs; 0/8 studies for Systemic glucocorticoids are from RCTs.

bDMARD, biological disease-modifying antirheumatic drug; csDMARD, synthetic disease-modifying antirheumatic drug; nr-axSpA, non-radiographic axial Spondyloarthritis; NSAIDs, non-steroidal anti-inflammatory drugs; r-axSpA, radiographic axial Spondyloarthritis; RR, relative risk.