Table 1.
Characteristics of patients with non‐small‐cell lung cancer and interstitial lung disease (ILD) at baseline (n = 94)
| No. of patients | (%) | |
|---|---|---|
| Gender | ||
| Male | 84 | (89) |
| Female | 10 | (11) |
| Age, y | ||
| Median (range) | 70 (54‐81) | |
| Performance status (ECOG) | ||
| 0 | 42 | (45) |
| 1 | 52 | (55) |
| Histology | ||
| Adenocarcinoma | 49 | (52) |
| Squamous cell carcinoma | 39 | (42) |
| Adenosquamous carcinoma | 2 | (2) |
| Others | 4 | (4) |
| Clinical stage | ||
| IIIA | 15 | (16) |
| IIIB | 23 | (24) |
| IV | 47 | (50) |
| Recurrence after surgical resection | 9 | (10) |
| ILD pattern on CT findings | ||
| UIP pattern | 50 | (53) |
| Possible UIP pattern | 44 | (47) |
| Inconsistent UIP pattern | 0 | |
| Severity of ILD | ||
| Mild | 67 | (71) |
| Moderate | 27 | (29) |
| Severe | 0 | |
| Patients with moderate ILD | ||
| %DLCO ≤ 50% | 15 | (17) |
| FVC < 65% | 6 | (6) |
| SpO2 on exertion < 88% | 6 | (6) |
| % predicted FVC, percent | ||
| Median (range) | 90.1 (53.2‐140.1) | |
| FEV1/FVC ratio, percent | ||
| Median (range) | 76.2 (48.1‐114.2) | |
| % predicted DLCO, percent | ||
| Median (range) | 63.7 (21.4‐116.1) | |
| PaO2, Torr | ||
| Median (range) | 82 (65‐116) | |
| KL‐6, U/mL | ||
| Median (range) | 672 (261‐4952) | |
Abbreviations: CT, computed tomography; DLCO, diffusing capacity of the lung for CO; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; SpO2, oxygen saturation; UIP, usual interstitial pneumonia.