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. 2019 Nov 8;8:e50063. doi: 10.7554/eLife.50063

Table 2. Predicted or known functions of screen candidates.

Gene Molecular function (based on information from Flybase) (Thurmond et al., 2019)
Atx-1 RNA binding
barc mRNA splicing; mRNA binding; U2 snRNP binding
bsf mitochondrial mRNA polyadenylation, stability, transcription, translation; polycistronic mRNA processing; mRNA 3'-UTR binding
CG16941/Sf3a1 alternative mRNA splicing; RNA binding
CG32364/tut translation; RNA binding
CG42458 mRNA binding
CG4849 mRNA splicing; translational elongation
CG5808 mRNA splicing; protein peptidyl-prolyl isomerization; regulation of phosphorylation of RNA polymerase II C-terminal domain; mRNA binding
CG6227 alternative mRNA splicing; ATP-dependent RNA helicase activity
CG7903 mRNA binding
CG8273/Son mRNA processing; mRNA splicing; RNA binding
CG8636/eIF3g1 translational initiation; mRNA binding
CG9609 transcription; proximal promoter sequence-specific DNA binding
Cnot4 CCR4-NOT complex
Dcp2 deadenylation-dependent decapping of mRNA; cytoplasmic mRNA P-body assembly; RNA binding
eIF1 ribosomal small subunit binding; RNA binding; translation initiation
eIF3l translational initiation
Hrb98DE translation; alternative mRNA splicing; mRNA binding
l(1)G0007 alternative mRNA splicing; 3'−5' RNA helicase activity
LSm7 mRNA splicing; mRNA catabolic process; RNA binding
ncm mRNA splicing; RNA binding
Nelf-A transcription elongation; RNA binding
Not1 translation; poly(A)-specific ribonuclease activity; CCR4-NOT complex
Not3 translation; transcription; poly(A)-specific ribonuclease activity; CCR4-NOT complex
Patr-1 cytoplasmic mRNA P-body assembly; deadenylation-dependent decapping of mRNA; RNA binding
Pcf11 mRNA polyadenylation; transcription termination; mRNA binding
pcm cytoplasmic mRNA P-body assembly; 5'−3' exonuclease activity
Psi alternative mRNA splicing; transcription; mRNA binding
Rga translation; transcription; poly(A)-specific ribonuclease activity; CCR4-NOT complex
RpS3 DNA repair; translation; RNA binding; structural constituent of ribosome
Rrp6 chromosome segregation; mRNA polyadenylation; nuclear RNA surveillance; 3'−5' exonuclease activity
sbr mRNA export from nucleus; mRNA polyadenylation; RNA binding
Set1 histone methyltransferase activity; nucleic acid binding; contains an RNA Recognition Motif
SmB mRNA splicing; RNA binding
SmE mRNA splicing; spliceosomal snRNP assembly
SmF mRNA splicing; spliceosomal snRNP assembly; RNA binding
smg RNA localization; translation; mRNA poly(A) tail shortening; transcription; mRNA binding
Smg5 nonsense-mediated decay; ribonuclease activity
Smn spliceosomal snRNP assembly; RNA binding
snRNP-U1-C mRNA 5'-splice site recognition; mRNA splicing, alternative mRNA splicing
Spx mRNA splicing; mRNA binding
Srp54k SRP-dependent cotranslational protein targeting to membrane; 7S RNA binding
Zn72D mRNA splicing; RNA binding