Table 4.
Antibiotic resistance pattern of DEC from case and control children younger than 5 years in Kano.
| Antibiotic | EAEC N (%) | EPEC N (%) | ETEC N (%) | Hybrid N (%) | Total DEC N (%) | DEC Negative | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Case (n = 79) |
Control (n = 11) |
Case (n = 13) |
Control (n = 2) |
Case (n = 39) |
Control (n = 4) |
Case (n = 34) |
Control (n = 1) |
Case (n = 165) |
Control (n = 18) |
Case (n = 50) |
Control (n = 15) |
|
| CXM | 12 (15.2) | 5 (45.5)* | 2 (15.4) | 2 (100.0) | 7 (17.9) | 1 (25.0) | 6 (17.6) | 1 (100.0)* | 27 (16.36) | 9 (50.0)* | 11 (22.0) | 6 (40.0) |
| CTX | 10 (12.7) | 0 (0.0) | 1 (7.7) | 0 (0.0) | 5 (12.8) | 1 (25.0) | 4 (11.8) | 1 (100.0)* | 20 (12.12) | 2 (11.11) | 11 (22.0) | 3 (20.0) |
| CAZ | 18 (22.8) | 6 (54.5)* | 2 (15.4) | 2 (100.0) | 8 (20.5) | 3 (75.0)* | 9 (26.5) | 1 (100.0) | 37 (22.4) | 12 (66.67)* | 11 (22.0) | 10 (66.7)* |
| AMC | 25 (31.6) | 9 (81.8)* | 5 (38.5) | 2 (100.0) | 19 (48.7) | 4 (100.0) | 17 (50.0) | 1 (100.0) | 66 (40.0) | 16 (88.9)* | 17 (34.0) | 10 (66.7)* |
| CIP | 6 (7.6) | 1 (9.1) | 0 (0.0) | 1 (50.0) | 1 (2.6) | 1 (25.0)* | 2 (5.9) | 0 (0.0) | 9 (5.45) | 3 (16.67) | 9 (18.0) | 1 (6.7) |
| CN | 3 (3.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (2.6) | 1 (25.0)* | 3 (8.8) | 0 (0.0) | 7 (4.24) | 1 (5.56) | 5 (10.0) | 1 (6.7) |
| SXT | 64 (81.0) | 8 (72.7) | 8 (61.5) | 2 (100.0) | 29 (74.4) | 2 (50.0) | 28 (82.4) | 1 (100.0) | 129 (78.18) | 13 (72.22) | 44 (80.0) | 6 (40.0) |
| Res. to 1 | 67 (84.8) | 10 (90.9) | 10 (76.9) | 2 (100) | 34 (87.2) | 4 (100.0) | 31 (91.2) | 1 (100.0) | 142 (86.06) | 17 (94.44)* | 47 (94.0) | 13 (86.67) |
| Res. to 2 | 27 (34.2) | 6 (54.5) | 0 (0.0) | 1 (50.0) | 15 (38.5) | 1 (25.0) | 15 (44.1) | 1 (100) | 57 (34.55) | 9 (50.0) | 14 (28.0) | 9 (60.0) |
| MDR | 5 (6.3) | 1 (9.1) | 0 (0.0) | 1 (50.0) | 2 (5.1) | 1 (25.0) | 3 (8.8) | 0 (0.0) | 10 (6.06) | 3 (16.67) | 7 (14.0) | 1 (6.67) |
DEC, Diarrheagenic E. coli; N, Number obtained; n, total number of DEC; %, Percentage; EPEC, Enteropathogenic E. coli; EAEC, Enteroaggregative E. coli Enterotoxigenic E. coli; CXM, Cefuroxime; CAZ, Ceftazidime; AMC, Amoxicillin-clavulanic acid; CIP, Ciprofloxacin; CN, Gentamycin; SXT, Trimethoprim-sulfamethoxazole; Res. to 1, 2, Resistant to at least 1 or at least 2 antibiotic classes; MDR, Multidrug Resistance;
*
P < 0.05.