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. 2019 Aug 7;30(1):383–393. doi: 10.1007/s00330-019-06380-9

Table 3.

Checklist for LIC evaluation

SIR methods

  • You could use several single-echo GRE but preferably ME-GRE to reduce the acquisition time, to be able to combine both methods and to quantify fat.

  • For Rennes algorithm (for both 1.5-T and 3-T systems), use the protocol described on the https://imagemed.univ-rennes1.fr/en/mrquantif/protocols.php web page. For SEDIA protocol at 1.5 T, global parameters are identical but only the two echoes at 4 and 14 ms TEs are used.

  • Use only body coil!

  • To get LIC preferably, use the DICOM software MRQuantif to have a control of the coil selected or go on-line to mrquantif.org or www.sedia.es

R2* methods

  • Use a 2D ME-GRE sequence (or several single-echo GRE if not available) and/or a vendor 3D ME-GRE optional sequence.

  • Check that the first echo is about 1 ms or even less.

  • Prefer a 2D ME-GRE sequence using body coil as described on the https://imagemed.univ-rennes1.fr/mrquantif/protocols if you are using a 3 T or dealing with highly overloaded patients

  • If you use a 2D ME-GRE sequence, choose your software option and the appropriate fit

  • Check that the R2* calculated is coherent with the liver signal

  • Select your R2* to LIC conversion formula

  • Mention the LIC and R2* values of spleen/pancreas in your report, define the thresholds for the clinicians