Table 4.
Proposition of a classification of iron overload severity
| Limits | Iron overload | Comment | ||
|---|---|---|---|---|
| Upper limit (× normal) | μmol/g (approximately) | mg/g (approximately) | ||
| < 1N | 0 to < 36 | 0 to < 2 | No | |
| < 2N | 36 to < 75 | 2 to < 4 | Insignificant | Usually with no treatment needed (except HH), follow-up |
| < 3N | 75 to < 100 | 4 to < 6 | Mild | Treatment depends on the patient profile |
| < 4N | 100 to < 150 | 6 to < 8 | Moderate | Treatment is usually performed (except hematologic causes) |
| < 8N | 150 to < 300 | 8 to < 16 | Moderate-severe | Corresponding usually only to HH or hematologic cause |
| ≥ 8N | ≥ 300 | ≥ 16 | Severe | With more cardiac risk |