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. 2019 Dec 3;9:18187. doi: 10.1038/s41598-019-54752-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Temperature-dependent hydrodynamic diameter evolution in water of (Ai) Ag@cur-P(MEO₂MA) B-series core-doped shell hybrid NPs (Table 1) and (Aii) cur-P(MEO₂MA) nanogels (Table 2) with different curcumin content. (B) ζ-potential determined by DLS at 10 °C and 35 °C for colloidal samples of (Bi) P(MEO₂MA) nanogels (G0), (Bii) AgNPs functionalized with 3.15 wt% curcumin content (Ag@cur) before and (Biii) after (MEO₂MA) polymerization, Ag@cur-P(MEO₂MA) hybrid NPs (Ag@cur-G3B). (C) UV-Vis spectra (below and above VPTT) of Ag@cur-P(MEO₂MA) hybrid NPs with Ag core synthesized at 90 °C (Ci) and 100 °C (Cii), and cur-P(MEO₂MA) nanogel (Ciii). All samples shown (C) were synthesized with 3.8 wt% curcumin/polymer ratio (Table 1 and Table 2).