Table 1.
Baseline characteristics
| Patient demographics | Pentaglobin (n = 10) | Placebo (n = 9) | p |
|---|---|---|---|
| Age (years) | 62 ± 20 | 67 ± 16 | 0.545 |
| Gender (nr of males, %) | 7 (70%) | 8 (89%) | 0.582 |
| Comorbidities (n, %) | 0.659 | ||
| Arterial hypertension | 4 (40%) | 3 (33%) | |
| Cardiopathy | 1 (10%) | 1 (11%) | |
| Diabetes | 2 (20%) | 1 (11%) | |
| Malignancy | 3 (30%) | 2 (22%) | |
| SAPS II (admission) | 42 ± 17 | 45 ± 12 | 0.690 |
| APACHE II (admission) | 17 ± 8 | 21 ± 7 | 0.243 |
| SOFA (admission) | 9 ± 4 | 10 ± 3 | 0.663 |
| Source of sepsis (n, %) | 0.532 | ||
| Abdominal | 4 (40%) | 2 (22%) | |
| Pulmonary | 3 (30%) | 2 (22%) | |
| Uro-genital | 1 (10%) | 3 (33%) | |
| Soft tissues | 1 (10%) | 2 (22%) | |
| Other | 1 (10%) | 0 (0%) | |
| Multi-drug-resistant pathogen (n, %) | 4 (40%) | 5 (56%) | 0.656 |
| Shocka (n, %) | 3 (30%) | 2 (22%) | 0.999 |
SAPS Simplified Acute Physiology Score, APACHE Acute Physiology and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment
aPersistent arterial hypotension despite adequate fluid resuscitation and hyperlactatemia (lactate levels > 2 mmol/L)