Table 4.
Oxygen duration, starting flow rate, and pre-treatment oxygen saturation (SpO2) among hypoxaemic children and neonates admitted to participating hospitals.
| Oxygen duration (days) | Starting flow rate (LPM) | Pre-treatment oxygen saturation (%) | Post-treatment oxygen saturation (%) | Mean volume of oxygen required (L) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | Median | IQR | Mean | Median | IQR | Mean | Median | IQR | Mean | Median | IQR | ||
| Overall | 2.8 | 1.5 | 0.5–3.5 | 1.1 | 1.0 | 0.5–1.0 | 74.6 | 81 | 67–88 | 94.6 | 96 | 94–98 | 4435 |
| Age group | |||||||||||||
| Neonates <28 days | 2.9 | 1.5 | 0.5–3.5 | 0.9 | 1.0 | 0.5–1.0 | 74.3 | 81 | 66–88 | 94.5 | 96 | 94–97 | 3758 |
| Infants 28 days to 1 year | 3.1 | 2.5 | 1.5–3.5 | 1.2 | 1.0 | 1.0–1.5 | 74.4 | 80 | 66.5–88 | 93.6 | 96 | 94–98 | 5356 |
| Children 1–4 years | 2.2 | 1.5 | 0.5–2.5 | 1.3 | 1.0 | 1.0–2.0 | 75.2 | 82 | 69–88 | 94.9 | 97 | 96–98 | 4118 |
| Children 5–14 years | 2.4 | 1.5 | 0.5–2.5 | 1.5 | 1.5 | 1.0–2.0 | 76.1 | 81.5 | 70.5–87 | 96.7 | 98 | 96–99 | 5184 |
| Condition | |||||||||||||
| ALRI | 3.2 | 2.5 | 1.5–3.5 | 1.3 | 1.0 | 1.0–2.0 | 74.8 | 81 | 68–88 | 94.3 | 96 | 94–98 | 5990 |
| AFE | 3.0 | 1.5 | 0.5–2.5 | 1.5 | 1.5 | 1.0–2.0 | 74.2 | 80.0 | 65–88 | 94.1 | 98 | 96–98 | 6480 |
| Malaria | 2.4 | 1.5 | 1.0–2.5 | 1.4 | 1.0 | 1.0–2.0 | 76.7 | 82 | 71–88 | 95.1 | 97 | 96–98 | 4838 |
| Diarrhoeal disease | 2.5 | 1.5 | 0.5–3.5 | 1.3 | 1.0 | 1.0–2.0 | 72.5 | 80 | 60–85 | 86.3 | 97 | 94–98 | 4680 |
| Sepsis | 2.6 | 1.5 | 0.5–3.5 | 1.2 | 1.0 | 1.0–2.0 | 75.8 | 82 | 68–88 | 93.9 | 97 | 95–98 | 4320 |
| Preterm | 4.0 | 2.5 | 1.5–4.5 | 0.8 | 0.5 | 0.5–1.0 | 75.6 | 82 | 68–89 | 95.4 | 96 | 94–97 | 4608 |
| Neonatal sepsis | 3.1 | 1.5 | 1.5–3.5 | 1.0 | 1.0 | 0.5–1.0 | 75.7 | 82.5 | 68–88 | 93.8 | 96 | 94–98 | 4464 |
| Neonatal encephalopathy | 2.7 | 1.5 | 1.5–3.5 | 0.9 | 1.0 | 0.5–1.0 | 73.8 | 80 | 66–88 | 94.3 | 96 | 94–97 | 3499 |
Analysis restricted to enhanced oxygen systems period to ensure limited supply did not prevent access. We report medians and interquartile ranges as the data is not normally distributed and report means for calculation total oxygen use (and easy comparison with previous studies). AFE = acute febrile encephalopathy; ALRI = acute lower respiratory infection; IQR = inter-quartile range, 25th75th centiles; LPM = litres per minute. Neonate = <28 days Mean volume of oxygen required assuming the starting flow rate is maintained throughout admission (i.e. mean oxygen duration x starting flow rate x 60 × 24).