Table 3.

Prevention matrix

Risk Factors	Domain	Protective Factors	Reference Nos.
Early aggressive behavior, dysregulated stress response, positive attitudes toward substance use, genetic risk, psychiatric disorder	Individual	Social competence, self-regulatory skills, school readiness, supportive parenting	41, 61, 135, 137, 233, 257, 258, 301
Harsh or absent parenting	Family	Positive parenting	42, 248
Antisocial influence	Peer	Positive peer networks	305
Poor classroom management, poor control of drug availability	School	Positive school environment, teacher behavior management competence	20, 110, 177, 191
Laws, policies, and perceived norms for substance use	Community	Community-level strategies to prevent substance use	44, 141