TABLE 2.

Characteristics of the 16 patients included in the pharmacokinetic study

Parameter	Value
Total no. of patients included	16
No. of male patients	6
No. of female patients	10
Age range (yr)	19–56
Median no. of CD4 cells/mm3 (IQRa )	28 (142–83)
No. (%) of patients with GCSb < 15	8 (50)
No. (%) of patients with CSF opening pressure of >20 cm H2O	10 (63)
Median baseline fungal burden (CFU/ml CSF) (IQR)	11,200 (390–63,000)
Mortality [no. (%) of patients who died/total no. of patients]
2 wk	1/16 (6)
10 wk	4/12 (33)c
1 yr	5/12 (42)

^aIQR, interquartile range.

^bGCS, Glasgow coma scale.

^cFour patients were lost to follow-up at between 2 and 10 weeks.