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K. pneumoniae-induced inflammation in the porcine EVLP model. mRNA levels in lung tissues mock infected (PBS) or infected with Kp52145 and strain 52145-ΔwcaK2 assessed by RT-qPCR. (A) il-6; (B) il-12; (C) il-8; (D) ifn-γ; (E) il-1β; (F) tnf-α; (G) nos2; (H) stat-4; (I) il-10. Values are presented as the means ± SEM from three independent experiments measured in duplicate. Statistical significance for the indicated comparisons was determined using one-way ANOVA with Bonferroni correction.
