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. 2018 Sep 11;39(12):2486–2496. doi: 10.1177/0271678X18800463

Table 3.

Results of linear regression analyses with lacunes on MRI as independent variable and total, periventricular or confluent WMH, and deep WMH volumes as dependent variables (all natural log-transformed).

Total Periventricular or confluent Deep
B (95% CI)a B (95% CI)a B (95% CI)a
No lacunes on MRI 0 (reference) 0 (reference) 0 (reference)
Lacunes on MRI 1.03 (0.86 to 1.21)b 1.08 (0.89 to 1.27)b 0.71 (0.44 to 0.97)b

WMH: white matter hyperintensity; MRI: magnetic resonance imaging; CI: confidence interval.

a

Adjusted for age, sex and total intracranial volume. B represents the natural log-transformed difference in volume between patients with and without lacunes on MRI.

b

p < 0.0001.