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. 2019 May 30;3(6):474–479. doi: 10.1002/jgh3.12183

Table 3.

Factors associated with complicated amoebic liver abscess(ALA)

Complicated (n = 68) versus uncomplicated (n = 130) ALA: comparison of variables Variables associated with complicated ALA
Parameter Results (mean ± SD, %) P‐value Univariate analysis (P‐value) Multivariate analysis (P‐value)
Age (years) 45.5 ± 11.4: 41.7 ± 12.3 0.030 0.030 0.004
Gender (M:F) ratio 66:2: 127:3 NS NS NS
BMI 20.5 ± 2.7: 20.9 ± 2.5 NS NS NS
Low socioeconomic status 89.7%: 86.9% NS NS NS
Duration of alcohol intake (years) 11.6 ± 7.5: 9.0 ± 7.3 0.021 0.034 0.040
Smoking 19.1%: 5.3% 0.001 0.001 0.007
Hemoglobin (gm/dL) 10.3 ± 2.3: 10.4 ± 1.7 NS NS NS
Leukocyte count (/mm3) 22 943 ± 11 005: 16 516 ± 7967 0.000 0.000 0.001
Platelet count (lakhs/mL) 2.8 ± 1.3: 2.9 ± 1.4 NS NS NS
Serum bilirubin (mg/dL) 3.3 ± 4.3: 2.0 ± 2.6 0.020 0.010 0.002
Protein (g/dL) 6.2 ± 1.2: 6.6 ± 1.1 NS NS NS
Albumin (g/dL) 2.5 ± 0.5: 2.9 ± 0.6 0.000 0.000 0.000
ALT (U/L) 86.9 ± 110.6: 69.8 ± 60.5 NS NS NS
AST(U/L) 98.2 ± 94.6: 80.3 ± 93.9 NS NS NS
ALP (IU/L) 469.6 ± 525.3: 412.5 ± 413.9 NS NS NS
Blood sugar (mg/dL) 101.4 ± 31.7: 107.8 ± 50.3 NS NS NS
Prothrombin time 1.2 ± 0.2: 1.2 ± 0.2 NS NS NS
Creatinine (mg/dL) 1.3 ± 0.9: 1.1 ± 0.8 NS NS NS
Sodium (mEq/L) 129.3 ± 7.8: 132.5 ± 6.0 0.006 0.003 0.005
Potassium (mEq/L) 4.0 ± 0.7: 4.0 ± 0.6 NS NS NS
Volume of abscess (mL) 542.3 ± 350.5: 436.1 ± 399.2 0.056 (NS) 0.046 0.153
Number of abscess 3.2 ± 3.5: 2.2 ± 2.3 0.041 NS NS
Hospital stay (days) 14 ± 6.8: 10.3 ± 3.9 0.000 NA NA
Duration of catheter insertion (days) 9.8 ± 8.9: 6.6 ± 3.6 0.020 NA NA

ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; ; INR, international normalized ratio; NA, not analyzed; NS, non‐significant.