Table 2.

Peak changes in PaCO₂ and PaO₂ during CO₂ and hypoxia trials testing arousal^a

		n	Hypercapnia		Hypoxia
			Δ PaCO2	Δ PaO2	Δ PaCO2	Δ PaO2
RTN-Control		5	20.9 ± 4	38.6 ± 5	−14.4 ± 3	−43.6 ± 8
RTN-Lesion		6–7	18.1 ± 5	30.6 ± 9	−16.5 ± 3	−33.3 ± 3*
CBx-Sham		5	11.6 ± 5	29.8 ± 14	−13.6 ± 2	−43.4 ± 6
CBx		5	16.8 ± 7	40.6 ± 6	−6.0 ± 3*	−47.0 ± 7
C1-Control		3	9.5 ± 3	27.6 ± 3	−10 ± 1	−36.6 ± 5
C1-Lesion		5	9.1 ± 4	29.8 ± 6	−13 ± 4	−45.0 ± 8

^aData are mean ± SD.

*p < 0.0001 for comparisons within the same experimental groups. RTN-Lesion versus RTN-Control during CO₂ trials, unpaired t test for PaCO₂, t₍₁₀₎ = 0.9, p = 0.37; PaO₂, t₍₁₀₎ = 1.8, p = 0.10. RTN-Lesion versus RTN-Control during hypoxia trials, unpaired t test for PaCO₂, t₍₉₎ = 1.1, p = 0.31; for PaO₂, t₍₉₎ = 2.8, p = 0.02. CBx-Sham versus CBx during CO₂ trials, unpaired t test for PaCO₂, t₍₈₎ = 1.3, p = 0.24; PaO₂, t₍₈₎ = 1.5, p = 0.19. CBx-Sham versus CBx during hypoxia trials, unpaired t test for PaCO₂, t₍₈₎ = 5.7, p = 0.0005; PaO₂, t₍₈₎ = 0.9, p = 0.40. C1-Control versus C1-Lesion during CO₂ trials, unpaired t test for PaCO₂, t₍₆₎ = 0.2, p = 0.88; PaO₂, t₍₆₎ = 0.06, p = 0.58. C1-Control versus C1-Lesion during CO₂ trials, unpaired t test for PaCO₂, t₍₆₎ = 1.5, p = 0.20; PaO₂, t₍₆₎ = 1.6, p = 0.16.