Figure 5.

IRt activity is required for coordination of fictive swallow. A, Under baseline conditions (gray), electrical stimulation of the SLN evoked apnea and rhythmic VNA (fictive swallows, orange circles). B, Swallow-triggered averages of rSNA and (C) rSNA autocorrelograms reveal swallow-related activity. Inhibition of the ipsilateral IRt reduced the number of fictive swallows (A, blue; pooled data in D) (significant differences identified using Wilcoxon matched-pairs signed rank test) and disrupted swallow-locked rSNA activity (C, blue) without inhibiting the apneic component of the response to SLN stimulation. ***p < 0.001.