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. 2019 Oct 24;218(12):3926–3942. doi: 10.1083/jcb.201810172

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© 2019 Roy et al.

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Figure 3. — Spc105^BPM suppresses defects in chromosome biorientation and error correction independently of Sgo1. Top: Schematic of the sister centromere cohesion and biorientation pathway in budding yeast. Bottom: Suppression of benomyl sensitivity by Spc105 BPM. Serial dilutions of yeast cells spotted on either rich medium or medium containing either 20 or 30 µg/ml benomyl. WT at the top of each plating indicates WT strain included as a positive control. WT, BPM, or ABPM in other rows refers to the Spc105 allele. spc105-6A, wherein all six MELT motifs are rendered nonphosphorylatable, was used as the negative control.