Table 1.
Selected characteristics of cancer cases and controls from the Linxian General Population Nutrition Intervention Trial, China (1986-2001)
| Variable | Esophageal squamous cell carcinoma | Gastric cardia adenocarcinoma | Gastric non-cardia adenocarcinoma | Upper gastrointestinal cancer | Control | P value |
|---|---|---|---|---|---|---|
| Number | 100 | 200 | 200 | 500 | 400 | |
| Age, mean (SD) | 52.8 (8.3) | 54.5 (8.1) | 56.1 (7.8) | 54.8 (8.1) | 51.1 (8.7) | <0.0001 |
| Sex, male, n(%) | 46 (46.0) | 117 (58.5) | 133 (66.5) | 296 (59.2) | 171 (42.8) | <0.0001 |
| Tobacco smokinga, n (%) | 34 (34.0) | 74 (37.2) | 95 (47.5) | 203 (40.7) | 125 (31.3) | 0.004 |
| Alcohol drinkingb, n (%) | 25 (25.0) | 39 (19.6) | 45 (22.5) | 109 (21.8) | 96 (24.1) | 0.4 |
| Family history of UGI cancer, n (%) | 36 (36.0) | 76 (38.2) | 63 (31.5) | 175 (35.1) | 116 (29.1) | 0.06 |
| Body mass index, mean (SD) | 21.7 (2.4) | 21.8 (2.3) | 21.4 (2.2) | 21.6 (2.3) | 22.0 (2.5) | 0.01 |
| H. pylori seropositivity, n (%) | 77 (77.0) | 153 (76.5) | 145 (72.5) | 375 (75.0) | 275 (68.8) | 0.04 |
| H. pylori CagA seropositivity, n (%) | 58 (58.0) | 149 (74.5) | 119 (59.5) | 326 (65.2) | 223 (55.8) | 0.004 |
| PG I/II ratioc, mean (SD) | 9.9 (5.9) | 8.2 (5.2) | 9.4 (10.2) | 9.0 (7.7) | 11.5 (10.6) | <0.0001 |
Note:
a,
tobacco smoking was defined as ever smoking cigarettes for 6 or more months;
b,
alcohol drinking was defined as any alcoholic beverage consumption in the last 12 months;
c,
PG I/II ratio, pepsinogen I/pepsinogen II ratio.