Table 1:
Characteristics of overall sample and the subsamples based on presence of restless legs syndrome.
| All Participants (N = 253) |
MS+RLS (n = 66) |
MS (n = 187) |
p-value | d | |
|---|---|---|---|---|---|
| Demographic and Clinical Characteristics | |||||
| Age (years) | 59.4 (10.0) | 59.1 (9.7) | 59.5 (10.1) | 0.758# | -- |
| Gender (n (%)) | 204 (80.6%) F / 49 (19.4%) M | 54 (81.8%) F / 12 (18.2%) M | 150 (80.2%) F / 37 (19.8%) M | 0.998+ | -- |
| Race (n (%)) | 0.422+ | -- | |||
| Black/African American | 4 (1.6%) | 0 (0.0%) | 4 (2.1%) | -- | -- |
| Caucasian | 239 (94.5%) | 65 (100.0%) | 174 (93.0%) | -- | -- |
| Latino/Latina | 5 (2.0%) | 0 (0.0%) | 5 (2.7%) | -- | -- |
| Other | 4 (1.6%) | 0 (0.0%) | 3 (1.6%) | -- | -- |
| MS Type (n (%)) | 0.731+ | -- | |||
| Relapsing-Remitting MS | 170 (67.2%) | 43 (65.2%) | 127 (67.9%) | -- | -- |
| Secondary Progressive MS | 51 (20.2%) | 14 (21.2%) | 37 (19.8%) | -- | -- |
| Primary Progressive MS | 29 (11.5%) | 9 (13.6%) | 20 (10.7%) | -- | -- |
| Benign | 3 (1.2%) | 0 (0.0%) | 3 (1.6%) | -- | -- |
| Disease Duration (years) | 20.3 (9.7) | 19.9 (10.1) | 20.4 (9.6) | 0.566# | -- |
| MS-specific DMT (n (%) Yes) | 184 (72.7%) | 47 (71.2%) | 137 (73.3%) | 0.676+ | -- |
| PDDS (median [IQR]) | 3.0 [8.0] | 3.0 [7.0] | 3.0 [8.0] | 0.300# | -- |
| IRLS | -- | 11.4 (7.6) | -- | -- | -- |
| PSQI | 7.2 (3.5) | 7.6 (4.0) | 7.1 (3.3) | 0.562# | 0.136 |
| Accelerometer Wear Time (min/day) | 807.3 (86.6) | 803.0 (83.1) | 808.8 (88.0) | 0.641 | 0.068 |
| Valid Days (number of days) | 5.9 (1.7) | 5.8 (1.8) | 5.9 (1.6) | 0.877# | 0.059 |
| Physical Activity Behavior | |||||
| LPA (min/day) | 243.9 (86.3) | 248.5 (79.9) | 242.3 (88.6) | 0.437# | 0.073 |
| MVPA (min/day) | 14.9 (20.8) | 14.9 (18.2) | 14.9 (21.6) | 0.742# | 0.000 |
| Active Bouts (#/day) | 0.3 (0.5) | 0.3 (0.6) | 0.2 (0.5) | 0.231# | 0.181 |
| Average Active Bout Length (min) | 4.2 (8.7) | 4.7 (8.1) | 4.0 (8.9) | 0.261# | 0.082 |
| Total time of Active Bouts (min/day) | 6.0 (13.9) | 6.3 (10.8) | 5.9 (14.9) | 0.287# | 0.031 |
| Sedentary Behavior | |||||
| Sedentary Behavior (min/day) | 548.5 (90.4) | 539.6 (78.6) | 551.6 (94.2) | 0.357 | 0.138 |
| Breaks in Sedentary Time (#/day) | 6.9 (1.9) | 6.8 (2.0) | 6.9 (1.9) | 0.857 | 0.051 |
| Average Sedentary Bout Length (min) | 49.7 (13.8) | 49.7 (11.7) | 49.7 (14.6) | 0.920# | 0.000 |
| Sedentary Bouts (#/day) | 6.1 (2.0) | 6.0 (2.0) | 6.1 (2.0) | 0.670 | 0.050 |
| Total time of Sedentary Bouts (min/day) | 304.4 (127.7) | 296.3 (120.1) | 307.2 (130.4) | 0.612# | 0.087 |
Note: Data are presented in mean ± standard deviation unless otherwise specified. MS multiple sclerosis; RLS restless legs syndrome; DMT Disease Modifying Therapies; PDDS Patient Determined Disease Status; IQR interquartile range; IRLS International Restless Legs Syndrome Study Group Scale; PSQI Pittsburgh Sleep Quality Index; LPA Light Physical Activity; MVPA Moderate-to-Vigorous Physical Activity.
#
Mann-Whitney U Test;
+
Chi Square Analysis