Table 3.
Association of baseline variables across all domains with time-to-flare following DMARD-cessation in a backward stepwise multivariate Cox regression model.
| Variable | B | HRflare | 95% CI | p |
|---|---|---|---|---|
| ENSG00000228010 | −1.972 | 0.14 | 0.05–0.37 | <0.001 |
| ENSG00000227070 | 1.080 | 2.95 | 1.73–5.01 | <0.001 |
| ACR/EULAR Boolean remission | −1.446 | 0.24 | 0.09–0.61 | 0.003 |
| ln(IL27 + 1) | 2.131 | 8.43 | 2.06–34.48 | 0.003 |
| FAM102B | 2.901 | 18.19 | 2.26–146.57 | 0.006 |
| RhF positive | 0.729 | 2.07 | 0.77–5.60 | 0.151 |
For continuous variables, hazard ratios (HR) and the Cox regression coefficients (B) are presented for a 1-unit change in that variable. Statistical significance calculated by the Wald test. ACR: American College of Rheumatology; CI: confidence interval; EULAR: European League Against Rheumatism; FAM102B: family with sequence similarity 102 member B IL: interleukin; RhF: rheumatoid factor.