Table 1.
Effect of DPHC on the deleterious changes in blood metabolic parameters in HFD-induced obese mice.
| Parameter | Group | ||
|---|---|---|---|
| HFD | HFD + DPHC25 | HFD + DPHC50 | |
| TG (mg/dL) | 137.88 ± 16.24 | 105.88 ± 4.09 * | 86.73 ± 11.03 ** |
| HDL-C (mg/dL) | 50.49 ± 3.10 | 60.93 ± 7.12 * | 72.71 ± 7.30 * |
| LDL-C (mg/dL) | 22.24 ± 1.40 | 18.07 ± 1.15 * | 16.82 ± 2.02 * |
| Leptin (ng/mL) | 2.04 ± 0.59 | 1.48 ± 0.42 | 1.23 ± 0.37 * |
| AST (mU/mL) | 47.11 ± 6.07 | 42.22 ± 3.74 | 41.02 ± 1.52 * |
Data are expressed as mean ± SD (n = 8). Significant differences compared with HFD mice group were identified at * p < 0.05 and ** p < 0.01. HFD: mice fed with high-fat diet; HFD + DPHC25: mice fed with HFD and 25 mg/kg body weight/day of DPHC; HFF + DPHC50: mice fed with HFD and 50 mg/kg body weight/day of DPHC; TG: Triglyceride; HDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; AST: aspartate transaminase.