Table 1.
Anti-inflammatory alkaloids from marine fungi.
| Metabolites | Species | Activities | Reference |
|---|---|---|---|
| Preussins C–K (1–9) | A. flocculosus 16D-1 | against IL–6 with IC50 values of 0.11–22 μM in LPS-activated THP-1 | [23] |
| Asperversiamides B, C, F, G (10–13) | A. versicolor | against iNOS with IC50 values of 5.39–16.58 μM in LPS-activated RAW264.7 cells | [24] |
| Luteoride E (14) | A. terreus | against NO with IC50 value of 24.65 μM in LPS-activated RAW264.7 cells | [25] |
| Chrysamide C (15) | P. chrysogenum SCSIO41001 | against IL–6 with 40.06% inhibitory at 1.0 μM | [26] |
| Viridicaol (16) | Penicillium sp. SF-5295 | against NO and PGE2 with IC50 values of 46.03 and 30.37 μM in LPS-activated RAW264.7 and 43.03 and 34.20 μM in LPS-activated BV2 cells | [27] |
| Brevicompanines E, H (17, 18) | Penicillium sp. | against NO with IC50 values of 27 and 45 μg/mL in LPS-activated RAW264.7 cells | [28] |
| Methylpenicinoline (19) | Penicillin sp. SF-5995 | against NO, PGE2, iNOS, and COX-2 with IC50 values from 34 to 49 μM | [29] |
| Neocechinulin A (20) | Eurotium sp. SF-5989 | significantly affection at concentrations exceeding 25 µM | [30] |