Effects of COS on hepatic steatosis in mice: (A) liver weight; (B) hepatic total cholesterol (TC); (C) hepatic triacylglycerol (TG); (D) hematoxylin and eosin (H&E) staining of liver sections (scale bar, 30 μm); (E) Oil Red O staining of liver sections (scale bar, 9 μm). Data are presented as the mean ± SE (n = 8 per group). Results were statistically analyzed using one-way ANOVA followed by Duncan’s multiple-comparison test, and values with different labels (a–c) are significantly different (p < 0.05). NCD, normal chow diet group; HFD, high-fat diet group; HFDLC, high-fat diet + low dosage of COS (200 mg/kg BW) group; HFDHC, high-fat diet + high dosage of COS (400 mg/kg BW) group; TC, total cholesterol; TG, triacylglycerol.