Effects of COS on the mRNA expression of genes related to hepatic lipid metabolism in mice: (A) SREBP-1c; (B) FAS; (C) PPARα; (D) CPT-1. Data are presented as the mean ± SE (n = 6 per group). Results were statistically analyzed using one-way ANOVA followed by Duncan’s multiple-comparison test, and values with different labels (a–c) are significantly different (p < 0.05). NCD, normal chow diet group; HFD, high-fat diet group; HFDLC, high-fat diet + low dosage of COS (200 mg/kg BW) group; HFDHC, high-fat diet + high dosage of COS (400 mg/kg BW) group. SREBP-1c, sterol regulatory element-binding protein-1c; FAS, fatty acid synthase; PPARα, peroxisome proliferator-activated receptor alpha; CPT-1, carnitine palmitoyltransferase 1.