Effects of COS on hepatic antioxidant indicators in mice: activities of T-AOC (A), GSH-Px (B), CAT (C), and SOD (D) in the liver; levels of MDA (E) and NO (F) in the liver. Data are presented as the mean ± SE (n = 8 per group). Results were statistically analyzed using one-way ANOVA followed by Duncan’s multiple-comparison test, and values with different labels (a–c) are significantly different (p < 0.05). NCD, normal chow diet group; HFD, high-fat diet group; HFDLC, high-fat diet + low dosage of COS (200 mg/kg BW) group; HFDHC, high-fat diet + high dosage of COS (400 mg/kg BW) group. T-AOC, total antioxidant capacity; GSH-Px, glutathione peroxidase; CAT, catalase; SOD, superoxide dismutase; MDA, malondialdehyde; NO, nitric oxide.