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. 2019 Nov 16;17(11):645. doi: 10.3390/md17110645

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of COS on hepatic protein expression in mice: (A) protein expressions of Nrf2, p-AMPK, AMPK, p-ACC, and ACC analyzed by the Western blot; density identification of Nrf2 (B), AMPK (C), and ACC (D). Data presented as the mean ± SE (n = 4−6 per group). Results were statistically analyzed using one-way ANOVA followed by Duncan’s multiple-comparison test, and values with different labels (a–c) are significantly different (p < 0.05). NCD, normal chow diet group; HFD, high-fat diet group; HFDLC, high-fat diet + low dosage of COS (200 mg/kg BW) group; HFDHC, high-fat diet + high dosage of COS (400 mg/kg BW) group. Nrf2, nuclear factor E2-related factor 2; AMPK, adenosine monophosphate-activated protein kinase; ACC, acetyl-CoA carboxylase.