Table 10.
Jejunal morphology and crypt cell proliferation of weanling pigs fed diets with mycotoxins (MT) or and YCWE1 (YC) in experiment 2.
| Mycotoxins (MT) | - | + | p Value | |||||
|---|---|---|---|---|---|---|---|---|
| YCWE (YC) | 0% | 0.2% | 0% | 0.2% | SEM | MT | YC | MT × YC |
| Villus height (VH), μm | 521 | 525 | 509 | 520 | 4.4 | 0.047 | 0.088 | 0.448 |
| Villus width (top), μm | 91 | 89 | 91 | 100 | 3.1 | 0.096 | 0.246 | 0.130 |
| Villus width (middle), μm | 118 | 113 | 111 | 114 | 3.3 | 0.401 | 0.673 | 0.258 |
| Villus width (bottom), µm | 124 | 119 | 121 | 117 | 4.3 | 0.476 | 0.257 | 0.870 |
| Crypt depth (CD), μm | 239 | 239 | 232 | 234 | 4.3 | 0.101 | 0.764 | 0.820 |
| VH-to-CD ratio2 | 2.19 | 2.20 | 2.20 | 2.23 | 0.04 | 0.759 | 0.632 | 0.788 |
| Ki-67, % | 26.0 | 28.7 | 22.0 | 26.5 | 2.01 | 0.091 | 0.052 | 0.646 |
1 YCWE: yeast cell wall extract; 2 Ki-67: technique for staining proliferating cells in the crypt where results are showed as a percentage of proliferating cells in comparison to all cells in the crypt. MT-: diet without aflatoxin B1 and fumonisin B1; MT+: inclusion of 180 μg/kg aflatoxin B1, 1 mg/kg deoxynivalenol, and 9 mg/kg fumonisin B1 by replacing the clean corn and clean wheat with naturally mycotoxin-contaminated corn and wheat; YC 0%: no addition of YCWE (Mycosorb A+, Alltech, Nicholasville, KY, USA); YC 0.2%: YCWE added at 2 g/kg of feed.