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. 2019 Oct 29;11(11):627. doi: 10.3390/toxins11110627

Table 1.

Secondary metabolites produced by Ascochyta and Phoma species.

Compounds Class Biological Function Producing Fungi (Host) [Reference]
ascochitine polyketide antifungal
phytotoxic
Ascochyta fabae (faba bean) [16,23,102]; A. hyalospora (lambsquarters) [25]; A. pisi (pea) [16,22]; A. salicorniae (Ulva sp., an alga) [27]; A. viciae-villosae (hairy vetch) [16,102]; Phoma clematidina (Clematis spp.) [24]; P. koolunga (pea) [16]; many Ascochyta-like spp. isolated from different legumes [16]
ascochlorin meroterpenoid antitrypanosomal A. viciae (Vicia spp., vetches) [56,64]
ascofuranone meroterpenoid antitrypanosomal A. viciae (Vicia spp., vetches) [57,65]
ascosalitoxin polyketide phytotoxic A. salicorniae (Ulva sp., an alga) [27]
brefeldin A polyketide phytotoxic P. medicaginis (Medicago spp.) [52]
cytochalasin A/B hybrid 1 cytotoxic A. lathyri (grass pea) [89]
herbarumin II polyketide phytotoxic A. pinodes (pea) [43,53]
lathyroxin A/B simple phenolics phytotoxic A. lentis var. lathyri (grass pea) [91]
lentiquinone A polyketide antibacterial (mild)
phytotoxic
A. lentis (lentil) [41]
lentiquinone C polyketide antibacterial
phytotoxic (mild)
A. lentis (lentil) [41]
lentisone polyketide antibacterial, phytotoxic A. lentis (lentil) [40]
pachybasin polyketide induction of mycoparasitic coiling A. lentis (lentil) [43]
pinolidoxin polyketide phytotoxic A. pinodes (pea) [16,42]; A. pinodella (chickpea, lentil) [16]
pseurotin A hybrid 1 phytotoxic (mild) A. lentis (lentil) [40]
putaminoxin polyketide phytotoxic A. pinodes (pea) [43]
pyrenolide A polyketide antifungal A. hyalospora (lambsquarters) [25]
solanapyrone A polyketide phytotoxic, antibacterial antifungal A. rabiei (chickpea) [16,47,70]
solanapyrone C polyketide algistatic, antibacterial A. rabiei (chickpea) [16,47,70]
tyrosol simple phenolics phytotoxic (mild)
quorum sensing
A. lentis (lentil) [40,92]

1 polyketide–nonribosomal peptide hybrid origin.