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. 2019 Nov 11;11(11):656. doi: 10.3390/toxins11110656

Figure 7.

Figure 7

A representation of the mode of action of squalamine antibacterial agent; intracellular ion efflux in Gram-positive bacteria caused by the depolarization of the membranes, and membrane disruption in Gram-negative bacteria. PG is peptidoglycan, CM is cytoplasmic membrane, and OM is outer membrane.