Table 2.
Toxicity Tests | CL Low (I) | CL Intermediate (II) | CL High (III) |
---|---|---|---|
Genetic toxicity tests | x | x | x |
Short-term toxicity tests with rodents | x | x | x |
Subchronic toxicity studies with rodents | x | x | |
Subchronic toxicity studies with non-rodents | x | x | |
One-year toxicity studies with non-rodents | x | ||
Chronic toxicity or Combined chronic toxicity/carcinogenicity studies with rodents | x | ||
Carcinogenicity studies with rodents | x | ||
Reproduction studies | x | x | |
Developmental toxicity studies | x | x | |
Metabolism and Pharmacokinetic studies | x | x | |
Human studies | x |